Manchester United have drawn Club Brugge in the last 32 of the Europa League, while Arsenal will face Champions League drop-outs Olympiakos.
Scottish champions Celtic are against FC Copenhagen, Rangers welcome Braga and Wolves will play Spanish side Espanyol.
The first legs will be played on February 20, with the second legs taking place seven days later on February 27.
The last-32 ties in full:
Wolves vs Espanyol
Sporting Lisbon vs Istanbul Basaksehir
Getafe vs Ajax
Bayer Leverkusen vs FC Porto
FC Copenhagen vs Celtic
Apoel vs FC Basel
Cluj vs Sevilla
Olympiacos vs Arsenal
AZ Alkmaar vs LASK
Club Brugge vs Manchester United
Ludogorets vs Inter Milan
Eintracht Frankfurt vs FC Salzburg
Shakhtar Donetsk vs Benfica
Wolfsburg vs Malmo
Roma vs Gent