The two Ghana Premier League giants will battle it out for the first silverware of the season later today in the President Cup to be held at the Accra Sports Stadium.
The game is a ceremonial one to honour sitting president Nana Akufo-Addo.
The bragging rights will be at stake in this game after the last meeting between the two teams in the Ghana Premier League a few days ago ended in a stalemate.
The game will be graced by President Nana Akufo-Addo and other high government officials and will see the two Ghanaian giants compete for the coveted trophy.
Asante Kotoko emerged winners in this game in 2019 and will be looking to defend their title against Hearts of Oak later today at the Accra Sports Stadium.
Heading into this crucial tie, the Porcupine Warriors are in top form, with Coach Prosper Narteh Ogum seeking for his first trophy with the club.
Kotoko are currently on top of the league table and is 14 points clear ahead of their arch-rivals Hearts of Oak.
The Porcupine Warriors also have the current leading top scorer in the Ghana Premier League Frank Etouga Mbella in their squad and the Cameroonian forward will be a major threat for the Hearts of Oak in this game.
However, Coach Samuel Boadu is yet to lose to Asante Kotoko in any competition since joining the club.
Hearts of Oak have been inconsistent this season and a chance to win this trophy can help revive their campaign.