The top liner for of Match Day four will see Medeama welcome Asante Kotoko to the Akoon Park.
Medeama who are considered red-hot favourites to win this season’s title dropped points away to Liberty Professionals on matchday three at the Carl Reindorf Sports Stadium at Dansoman after a 1-1 draw on Sunday.
Asante Kotoko, on the other hand, lost at home to Berekum Chelsea by a lone goal.
The two sides will be hoping to recover those lost points when both teams face off in this crucial fixture.
In the last meeting between both sides in the NC Special Competition, Asante Kotoko lost to Medeama by a lone goal at the Tarkwa and Aboso Park.
The game which will be played at the Akoon Park due to renovation works ongoing at the Tarkwa and Aboso Park will see the two teams battle it out on neutral ground for the first time.
Asante Kotoko will be searching for their first win over Medeama in the league.
Matchday four fixtures at a glance
Eleven Wonders vs Aduana Stars
Great Olympics vs Karela
Ebusua Dwarfs vs Liberty Professionals
Medeama vs Asante Kotoko
Inter Allies vs Elmina Sharks
WAFA vs Hearts of Oak
King Faisal vs Bechem United
Berekum Chelsea vs Dreams
Legon Cities vs AshantiGold